Alpha-fetoprotein-L3 and Golgi protein 73 may serve as candidate biomarkers for diagnosing alpha-fetoprotein-negative hepatocellular carcinoma
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چکیده
منابع مشابه
Alpha-fetoprotein-L3 and Golgi protein 73 may serve as candidate biomarkers for diagnosing alpha-fetoprotein-negative hepatocellular carcinoma
Currently, there is no reliable biomarker for use in diagnosing alpha-fetoprotein (AFP)-negative hepatocellular carcinoma (HCC). Such a biomarker would aid in making an early diagnosis of AFP-negative HCC, ensuring the timely initiation of treatment. This study examined AFP-L3 and Golgi protein 73 (GP73) as candidate biomarkers for AFP-negative HCC. The affinity adsorption method and enzyme-lin...
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Japan is the only country where alpha-fetoprotein (AFP)-L3 can be measured in the routine clinical setting. Since AFP-L3 examination has been covered by health insurance in Japan for over 10 years, it is now routinely measured during general medical checkups for patients with chronic liver disease. To increase the specificity of AFP, the AFP-L3 glycoform can be used as a measure of cancerous ch...
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Conflicting results have been widely reported on the use of Golgi protein 73 (GP73) as a serum biomarker for diagnosing hepatocellular carcinoma (HCC). This study evaluated the accuracy of GP73, alpha-fetoprotein (AFP), and GP73 + AFP for diagnosing HCC. The meta-analysis was performed on 11 studies that were selected by means of a comprehensive systematic literature review. Summary diagnostic ...
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ژورنال
عنوان ژورنال: OncoTargets and Therapy
سال: 2015
ISSN: 1178-6930
DOI: 10.2147/ott.s90732